Fury Indah, Evi Hasnita, Nurdin Nurdin


Postpartum haemorrhage is the most common cause of all deaths from obstetric haemorrhage. Postpartum haemorrhage is bleeding that exceeds 500 ml after the baby is born in vaginal delivery and exceeds 1000 ml in cesarean section or bleeding that is more than normal which has caused changes in vital signs. The purpose of this study was to determine the determinants of postpartum hemorrhage from national and international research publications with meta-analyses. Identify study articles by searching through Pubmed, Springer Link, Google Scholar database searches on the internet. Assessment of the quality of the studies included in this study were selected in advance, the selected journals were publication journals that were relevant to the research question, original research (original), indexed Scopus Q1, Q2, Q3, Q4 and indexed Sinta (S1, S2). The research study used was an observational cohort, case-control and cross-sectional design study. Statistical analysis using the fixed effect model or random effect model to see the estimated specific effect and the combined determinants of postpartum hemorrhage and sensitivity test to see the stability of the variables to changes. Data analysis software uses RevMan 5.4. The results showed that there were 13 countries out of 20 selected journals, the estimation of the determinant effect of Postpartum Hemorrhage in Asia from the meta analysis obtained age had an OR of 2.52 (95% CI: 1.83-3.47). Parity has an OR of 2.54 (95% CI: 1.22-5.31). Anemia has an OR of 3.43 (95% CI: 1.65-7.11). History of childbirth has an OR of 3.40 (95% CI: 2.62-4.42). Stress has an OR of 2.06 (95% CI: 0.46-9.31). Education has an OR of 1.27 (95% CI: 0.23-6.94). Lifestyle has an OR of 1.48 (95% CI: 0.85-2.22). It was concluded that the determinant of postpartum hemorrhage in Asia was anemia with the highest OR of 3.43. It is hoped that this can be used as a guideline for stakeholders in the health sector in determining program priorities to prevent and control postpartum hemorrhage problems. The results of the research can directly provide knowledge to the public about the determinants of postpartum hemorrhage and how to manage pressure to control and avoid postpartum hemorrhage

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Anna. 2020. Stress and Anxiety Levels in Pregnant and Post-Partum Women during the COVID-19 Pandemic. Int. J. Environ. Res. Public Health 2020, 17, 9450

Amir. 2017. Barriers or gaps in implementation of misoprostol use for post-abortion care and post-partum hemorrhage prevention in developing countries: a systematic review. Systematic Review.

Chang Xu (2020). Differential effects of different delivery methods on progression to severe postpartum hemorrhage between Chinese nulliparous and multiparous women: a retrospective cohort study. BMC Pregnancy and Childbirth. Vol 20. Pp: 1-13.

Chien Yu Lin (2018). Postpartum Depression and Subsequent Autoimmune Diseases in Taiwan. Int. J. Environ. Res. Public Health. Vol. 15, 1-10.

Cherlyen Teo (2018). Prospective Associations of Maternal Dietary Patterns and Postpartum Mental Health in a Multi-Ethnic Asian Cohort: The Growing up in Singapore towards Healthy Outcomes (GUSTO) Study. Nutrient. Vol. 10, pp: 1-9

Begg, C. B., Cooper, H., & Hedges, L. V. (1994). The handbook of research synthesis. Russell Sage Foundation.

Bernasconi. 2021. Paternal and maternal long‑term psychological outcomes after uterine artery embolization for severe post‑partum hemorrhage. Scientific Reports (2021) 11:13990

Brahmana, Beru, Ivana. 2018. Perdarahan Pasca Persalinan Oleh Karena Retensio Plasenta Pada Perdarahan Postpartum Spontan, Janin Besar, dengan Hipertensi dalam Kehamilan: Jurnal Kedokteran Dan Kesehatan. 18 (1). 30-40

Dede. 2020. Meta-Analisis Determinan Hipertensi Di Asia Tahun 2020. Tesis

Defi Uprianti Bakri, Syahredi S. Adenin , Irza Wahid. 2019. Faktor- Faktor Yang Berhubungan Dengan Kejadian Perdarahan Postpartum Pada Ibu Bersalin di Wilayah Kerja Dinas Kesehatan Kabupaten Merangin; Dinamika Kesehatan Jurnal Kebidanan dan Keperawatan Vol 10 No. 2 Desember 2019.

Devendra et al. (2021). Determining factors for the prevalence of depressive symptoms among postpartum mothers in lowland region in southern Nepal. Plos One, Vol. 16 (1). Pp: 1-16.

Dharmadi, Buntoro Indra. 2017. Hubungan Kejadian Perdarahan Postpartum dengan Karakteristik Ibu Bersalin di RB Harapan Kita. Jurnal Bimtas.

Egenberg, Signe. 2017. Impact of multi-professional, scenariobased training on postpartum hemorrhage in Tanzania: a quasi-experimental, pre- vs. postintervention study. Tanzania. BMC Pregnancy and Childbirth

Fitriwati. 2019. Factors Related to Postpartum Hemorrhage Occurrence in Lubuk Gadang Public Health Center Sangir District South Solok Regency Year 2019. Skripsi

Frisca, Rully and Rochany (2019) Identifikasi Faktor Ibu Dengan Perdarahan Postpartum; Oksitosin: Jurnal Ilmiah Kebidanan, Vol. 6, No. 2, Agustus 2019 : 119-126

Friyandini F, Lestari Y., Utama BI. 2015. Hubungan Kejadian Perdarahan Postpartum dengan Faktor Risiko Karakteristik Ibu di RSUP Dr. M. Djamil Padang pada Januari 2012 - April 2013. Padang. Jurnal Kesehatan Andalas

Holly B Ende et al (2021) Risk Factors for Atonic Postpartum Hemorrhage, Obstetrics and Gynecology, United State

Jahirul Islam et al (2021). Early exclusive breastfeeding cessation and postpartum depression: Assessing the mediating and moderating role of maternal stress and social support. Plos One. Vol 16 (5), pp: 1-19.

Jannah (2022). The Relationship of Physical Exercise with Postpartum Depression. Jurnal Kesehatan, Volume 13, Nomor 2, Tahun 2022

Kacou Edele et al (2017) A rare case of important and recurrent abnormal uterine bleeding in a Postpartum woman caused by cavernous hemangioma: a case report and review of literature, The Pan African Medical Journal

Kemenkes R.I., 2019. Kematian Maternal dan Neonatal di Indonesia. Kementerian Kesehatan RI

Keiko. (2021). Associations of education and income with hazardous drinking among postpartum women in Japan: results from the TMM BirThree Cohort Study. Environmental Health and Preventive Medicine. Vol. 26. Pp: 1-10.

Kenneth et al (2021) Healthcare providers experiences of using uterine balloon tamponade (UBT) devices for the treatment of post-partum haemorrhage: A meta-synthesis of qualitative studies, Plos One USA

LeMaster (2021). Adverse childhood experiences and depression among women in rural Pakistan. BMC Public Health . Vol. 21. Pp: 1-11.

LeMaster (2020). Maternal depression in rural Pakistan: the protective associations with cultural postpartum practices. BMC Public Health . Vol. 20. Pp: 1-12.

Mwashamba et al (2020). Prevalence and risk factors associated with severe pre-eclampsia among postpartum women. BMC Publich Health. Vol 20. 1-10

Nyflot (2017). Risk factors for severe postpartum hemorrhage: a case-control study. BMC Pregnancy and Childbirth. 17:17, pp: 1-9.

Park (2017). A history of repetitive cesarean section is a risk factor of anemia in healthy perimenopausal women: The Korea National Health and Nutrition Examination. Plos One, Vol 12 (11), pp: 1-11.

Phat. (2020). Maternal and health service predictors of postpartum hemorrhage across 14 district, general and regional hospitals in Thailand. BMC Pregnancy and Childbirth. Vol. 20, pp: 1-12.

Psiari Kusuma Wardani. 2017. Faktor Yang Mempengaruhi Terjadinya Perdarahan Pasca Persalinan; Jurnal Ilmu Kesehatan 2 (1) 2017, 51-60.

Prawirohardjo. 2016. Ilmu Kebidanan. Jakarta: Bina Pustaka

Piscolia Dynamurti Wintoro. 2021. Implementasi Sistem Rujukan Pada Kasus Perdarahan Post Partum Primer Oleh Bidan Desa Di Wilayah Kerja Puskesmas Bayat, Kabupaten Klaten; Naskah Publikasi

Rahayu Eka P Lestari., Hidayah W., Sholiha M. 2014. Hubungan Paritas dengan Kejadian Perdarahan Postpartum pada Ibu Bersalin. Bojonegoro. Jurnal Penelitian Kesehatan

Saralee (2018). The tip of the iceberg: postpartum suicidality in Israel. Israel Journal of Health Policy Research. Vol. 7

Sarah and Joseph. 2020. Laboratory monitoring during pregnancy and post-partum hemorrhage in women with von Willebrand disease; J Thromb Haemost. 2020;18:604–608

Shicun Cen et al (2019) Traditional Chinese Medicine Yimucao Injection Combined with Western Medicine for Preventing Postpartum Hemorrhage after Cesarean Section, Evidence-Based Complementary and Alternative Medicine

Stepan et al (2020), Epidemiology, prevention and management of early postpartum hemorrhage, Via Medica

Waraporn et al. (2021). Risk Factors for Postpartum Hemorrhage in a Thai–Myanmar Border Community Hospital. Int. J. Environ. Res. Public Health. Vol 18, pp: 1-13.

Williams Obstretics 21 st Ed: F.Gary Cunningham (Editor), Norman F.Grant MD,Kenneth J,.,Md Leveno, Larry C.,Iii,Md Gilstrap,John C.,Md Hauth, Katherine D.,Clark,Katherine D.Wenstrom,by McGraw-Hill Profesional (April 27,2001)

Wardani, Psiari Kusuma. 2017. Faktor-faktor yang Mempengaruhi Terjadinya Perdarahan Pasca Persalinan. Jurnal Ilmu Kesehatan. 2(1),51-60.

Yekti Satriyandari, Nena Riski Hariyati. 2017. Faktor-Faktor Yang Mempengaruhi Kejadian Perdarahan Postpartum; Journal of Health Studies, Vol. 1, No.1, Maret 2017: 49-64

Yushan et al (2020) se of nitroglycerin for parallel transverse uterine cesarean section in patients with pernicious placenta previa and placenta accrete and predicted difficult airway, Baltimore, Philadelphia

Yu Wang (2021). Ethnic disparities in postpartum hemorrhage after cesarean delivery: a retrospective case–control study. Journal of Anesthesia. 35:197–205



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